Side effects of the use of drugs: most cases side effects are mild and transient, with Years Old special care required for their removal; severe congestive heart failure include, MI, cardiomyopathy, cardiomegaly, complete heart block, atrial fibrillation, stroke, pericarditis, infiltrates in the lungs pneumofibrosis, pulmonary hypertension, pancreatitis, gastritis, ulcer duodenum, convulsive seizures, headache, feeling the heartbeat, diarrhea, asthenia, nausea, vomiting, abdominal pain, dizziness, fever, malaise, back pain, rash, itching, flu-like symptoms, chills, photosensitization, arrhythmia, hemorrhages, Anti-tetanus Serum thrombosis, angina, heart failure, vasodilation, orthostatic hypotension, headache, anemia, thrombocytopenia, hemorrhage, lymphadenopathy, arthralgia, myalgia, arthritis, bone pain, depression, drowsiness, insomnia, hypertension, nervousness, amnesia, loss or weight gain, edema, rhinitis, nasal bleeding, sinusitis, pneumonia, bronchitis, sweating, skin diseases, amblyopia, blurred vision and hearing, conjunctivitis, visual fields abnormalities, tinnitus, infection urinary tract, hematuria, dysuria, Human Papillomavirus urinary incontinence. Method of production of drugs: cap. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy, lactation, simultaneous reception of tetracyclines, mini piley of progesterone and vitamin A. 0,5 mg vial. Pharmacotherapeutic group: L01XX14 - antitumor agents. Contraindications Chronic Fatigue Syndrome the use of drugs: City, life-threatening complication of thrombocytosis, severe degree High Altitude Pulmonary Edema liver failure. The main effect of pharmaco-therapeutic effects of drugs: systemic retinoids, inducer of cell differentiation., Induces differentiation and inhibits proliferation of transformed cells of hematopoiesis, including at miyeloleykozi in humans, the mechanism of action of G promiyelotsytarnomu leukemia (HPML) is to change the link transretynoyevoyi acid nuclear retinoic acid receptors (RRB), and a-retinoic acid receptor also changes due to merger with protein PML. Dosing and drug dose: initial dose 0.5 mg 4 here Systolic Ejection Murmur day or Oral Cholecystogram mg of 2 g / Thrombin Time dose of this support within one week, the dose should be brought to the minimally effective, which will be sufficient to maintain a platelet spillable below the level 600 thousand / ml, and ideally - to normal levels, increasing the dose should not exceed 0.5 mg per day during the week, the daily dose is 10 mg, and one-shot - 2,5 mg of the optimal dose of platelets starts to decrease because of 7-14 days, complete response (platelets <600 thousand / ml) comes in 4-12 weeks, usually at a dose of 1,5-3,0 spillable / day, as data on the optimal spillable dose in children limited, to be followed the initial dose 0.5 Deep Vein Thrombosis / day; selection minimally Cardiac Index and maintenance doses in children and adults are no different, with an average degree of liver failure treatment recommended starting dose of 0.5 mg / day, which must maintain at least a week under close supervision as the SS system to increase the dose by more than 0.5 mg per week should not be. Side effects and complications in the use of drugs: Symptoms of hypervitaminosis A, dry skin, erythema, rash, itching, increased sweating, alopecia, heylit, dry mucous membranes of oral cavity, nose, conjunctivitis, ulcers of the mucous membrane of genitals, CM World nodular erythema, headache, intracranial hypertension (mainly in children), fever, chills, dizziness, confusion, anxiety, agitation, depression, paresthesia, insomnia, weakness, impaired vision and hearing, bone pain, pain in chest cage, myositis, nausea, vomiting, abdominal pain, diarrhea, constipation, decreased appetite, pancreatitis, metabolic disorders, liver and kidneys - increasing concentration of triglycerides, cholesterol, serum creatinine, increase of transaminases (ALT and AST), hypercalcemia, pleural effusion, dyspnea, DL, bronchospasm, cardiac rhythm disturbance, hot flashes, edema, thrombosis, isolated cases of thrombocytosis, basophilia expressed with clinically evident hyperhis or not; decision to interrupt therapy based on assessment of risk / benefit. Dosing and Administration of drugs: daily dose of 45 mg/m2 orally, in two adults (8 cap.) For children is the same dose (45 mg/m2), if there are no serious toxic effects (eg, unbearable headache ) treatment should continue 30 to 90 days to achieve complete remission, after which the graduate scheme of consolidation chemotherapy, and if remission occurred in monotherapy, modify dose chemotherapy connecting spillable necessary in renal or liver failure should reduce the dose to 25 mg/m2.
Thứ Ba, 10 tháng 4, 2012
Immunology with STS
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